Hi! I just saw a show on this tonight. Here is a link and a part of the article. It is fastinating scientific evidence about the effect of diet not only on us but on future generations.
“they did not display their parentsâ€™ susceptibility to cancer and diabetes and lived to a spry old age. The effects of the agouti gene had been virtually erased.
Remarkably, the researchers effected this transformation without altering a single letter of the mouseâ€™s DNA. Their approach instead was radically straightforwardâ€”they changed the momsâ€™ diet.
Starting just before conception, Jirtle and Waterland fed a test group of mother mice a diet rich in methyl donors, small chemical clusters that can attach to a gene and turn it off. These molecules are common in the environment and are found in many foods, including onions, garlic, beets…something as subtle as a nutritional change in the pregnant mother rat could have such a dramatic impact on the gene expression of the baby,â€ Jirtle says. â€œThe results showed how important epigenetic changes could be.â€
Our DNAâ€”specifically the 25,000 genes identified by the Human Genome Projectâ€”is now widely regarded as the instruction book for the human body. But genes themselves need instructions for what to do, and where and when to do it. A human liver cell contains the same DNA as a brain cell, yet somehow it knows to code only those proteins needed for the functioning of the liver.
Those instructions are found not in the letters of the DNA itself but on it, in an array of chemical markers and switches, known collectively as the epigenome, that lie along the length of the double helix. These epigenetic switches and markers in turn help switch on or off the expression of particular genes. Think of the epigenome as a complex software code-
more here: http://www.geneimprint.com/media/pdfs/116233491…